PRP Chitetezo ndi Kudalirika

Kodi PRP ndi yodalirika bwanji?

PRP imagwira ntchito mwa kuwonongeka kwa tinthu tating'ono ta alpha m'mapulateleti, omwe amakhala ndi zinthu zina zakukulira.PRP iyenera kukonzedwa mumtundu wa anticoagulant ndipo iyenera kugwiritsidwa ntchito pazitsulo, zophimba, kapena mabala mkati mwa mphindi 10 kuchokera pamene magazi ayamba.

Pamene mapulateleti amayendetsedwa ndi kutsekeka, zinthu zakukulira zimatulutsidwa kuchokera ku selo kudzera mu nembanemba ya cell.Pochita izi, tinthu tating'onoting'ono ta alpha timaphatikizana ndi nembanemba zama cell cell, ndipo kukula kwa mapuloteni kumamaliza bioactive state powonjezera unyolo wam'mbali wa histone ndi carbohydrate ku mapuloteniwa.

Kafukufuku wasonyeza kuti munthu wamkulu mesenchymal tsinde maselo, osteoblasts, fibroblasts, endothelial maselo, ndi maselo a epidermal amaonetsa cell membrane zolandilira zinthu kukula mu PRP.Ma transmembrane receptors nawonso amapangitsa kuyambitsa kwa mapuloteni olowa mkati omwe amatsogolera ku kufotokozera (kutsegula) kwamayendedwe amtundu wa cell, monga kuchuluka kwa ma cell, mapangidwe a matrix, mapangidwe a osteoid, kaphatikizidwe ka collagen, ndi zina zambiri.

Choncho, kukula kwa PRP sikulowa mu selo kapena phata lake, si mutagenic, iwo amangofulumizitsa kulimbikitsa machiritso abwino.

Pambuyo pa kuphulika koyamba kwa zinthu zomwe zimayenderana ndi kukula kwa PRP, mapulateleti amapangidwa ndikutulutsa zinthu zina zakukula kwa masiku 7 otsala a moyo wawo.Mapulateleti akatha ndi kufa, ma macrophages omwe amafika m'derali kudzera m'mitsempha yamagazi yolimbikitsidwa ndi mapulateleti amakulira mkati kuti atenge gawo lowongolera machiritso a zilonda pobisa zinthu zina zomwe zimakula komanso zina.Motero, kuchuluka kwa mapulateleti amene ali mu phata, pabala, kapena magazi amene amaundana pa nthitiyo amatsimikizira mmene balalo limachira msanga.PRP imangowonjezera nambala imeneyo.

1) PRP ikhoza kupititsa patsogolo maselo amtundu wa fupa m'mafupa ogwidwa ndi mafupa ndikulimbikitsa mapangidwe a mafupa.PRP imakhalanso ndi zinthu zosiyanasiyana za kukula, zomwe zingalimbikitse kugawanika kwa maselo ndi kusiyanitsa ndi kulimbikitsa kukonzanso thupi.

2) Ma leukocyte mu PRP amatha kupititsa patsogolo mphamvu yolimbana ndi matenda a malo ovulala, kuthandizira thupi kuchotsa minofu ya necrotic, ndikufulumizitsa kukonzanso chovulalacho.

3） PRP ili ndi kuchuluka kwa fibrin, yomwe imatha kupanga nsanja yabwino yokonzanso thupi ndikuchepetsa mabala nthawi imodzi.

Kodi PRP ndi yotetezeka komanso yothandiza?

1) Zopangidwa ndi magazi zokha

Deta yochuluka yoyesera yasonyeza kuti PRP ikhoza kusonyeza chitetezo chake ndi kudalirika kwa mankhwala ambiri.Monga mankhwala a magazi a autologous, PRP imapewa bwino kukana ndi kufalitsa matenda chifukwa cha kugwiritsa ntchito magazi a allogeneic panthawi ya chithandizo.

2）Woyambitsa coagulation ndiwotetezeka

PRP imagwiritsa ntchito bovine thrombin monga coagulation initiator, kuthandizira kutulutsa PRP panthawi imodzi ndi opaleshoni.Bovine thrombin yomwe imagwiritsidwa ntchito ndi kutentha ndipo simayambitsa matenda.Ndipo chifukwa kuchuluka kwa thrombin ya bovine yomwe imagwiritsidwa ntchito ndi yaying'ono kwambiri, sikulowa m'thupi ndikuyambitsa kukanidwa pakagwiritsidwa ntchito.

3) Zogulitsa ndizotetezeka komanso zothandiza

Njira za Aseptic zimagwiritsidwa ntchito pokonzekera PRP, zomwe zimapangitsa kuti magazi azikhala ndi magazi omwe samayambitsa matenda ndipo samayambitsa kukula kwa bakiteriya.

(Zomwe zili m'nkhaniyi zidasindikizidwanso, ndipo sitikupereka chitsimikizo chotsimikizika kapena chotsimikizika pakulondola, kudalirika kapena kukwanira kwa zomwe zili m'nkhaniyi, ndipo sitili ndi udindo pamalingaliro ankhaniyi, chonde mvetsetsani.）